Valladolid is generally considered safe, even during the night. However, as in any other city in the world, it is not entirely risk-free. It's a small city with a significantly lower crime rate compared to other parts of Mexico. The locals are friendly and helpful, but it's always important to be cautious and aware of your surroundings, especially if you are walking alone. As a standard rule, sticking to well-lit, populated areas and avoiding unnecessary travel after dark is recommended. Police presence is usually visible throughout the city, adding an extra layer of safety for tourists.