Punta Sam is generally considered quite safe for solo female travelers. Locals are friendly and respectful towards tourists. However, like anywhere else in the world, it's always important to exercise common sense and precautions. Stick to well-populated, tourist-friendly areas, avoid venturing out alone at night, and always keep an eye on your personal belongings. As with any travel destination, it's also wise to learn about any current safety issues or advisories before your visit.