Pilsen is amazing city overall very safe. People are friendly but at night in some places it can get a bit crazy. Avoid walking in parks at night alone and avoid the Americká street. Often you will meet weird people around train station.

I live here for almost three months and i didn’t see anyone is hurting another . But my czech friends always say dont go to borsky park alone at night. Otherwise Pilsen is really safe for women and solo travellers

I would say its pretty safe. As long as you’re not alone in the middle of the night on Americka street or in the area you should be good. But you can never be sure, so if possible be aware of your surroundings and take a friend or two with you. Stay safe!

The only time I feel unsafe is when travelling alone after dark, but if you're with multiple girlfriends, or even one friend, you'll feel safe, or anyone any gender! I feel very safe using public transport, there is always a lot of people around in case something happens