Is Brno Safe for Solo Female Travelers?

As always, it depends on which part of the city you're in. In daylight I wouldn't be worried anywhere, at night/when it gets dark I wouldn't recommend going through Cejl or being at main train station alone. Not that anything would happen to you, but some really weird individuals are there at night and I personally feel uneasy traveling through there alone at night. Ignore drunks and ignore sketchy looking people. Czechs aren't usually very talkative with strangers, so some random person talkig to me on the street would raise some red flags for me (but in bars/clubs/pubs or other social spaces people can be friendly)

I would say that Brno is quite save place. You just need ti svoje certain places at night (main train station and a pls d called "Cejl") and watch your stuff. Im not usually worried at night going by myself home.

Solo travel experience

I loved Brno and I really enjoyed it there. Great shopping, food, very affordable prices, beautiful cathedral, cool castle, and excellent beers. The old town is beautiful.