Podebrady is a charming and peaceful spa town that is generally very safe for solo female travelers. The low crime rate makes it a secure place for exploration and enjoying the local culture. The locals are friendly and helpful, and most of them speak English, which would make your communication fairly easy. Transport is reliable and safe as well. It's always recommended to use common travel sense like not wandering off alone late at nights and keeping your belongings secure just as a precautionary measure, but overall, Podebrady leaves little room for safety concerns.