Ceske Budejovice, in the Czech Republic generally presents a safe environment for solo female travelers. The city is known for its welcoming and friendly residents and its low crime rate. However, being the largest city in the South Bohemian Region, there could be instances of petty crime such as pickpocketing particularly in busy touristic spots. It's largely safe to walk around even at night. Regardless, it's always recommended to follow the usual diligence and safety protocols - staying alert, keeping expensive items hidden, and avoiding unfamiliar or isolated areas during late hours. Public transports are considered reliable and safe too, especially in the daytime. Beyond this, the locals are known to willingly offer assistance if needed.