Mazatlan carries a moderate level of safety for solo female travelers. While it is a popular city known for its beautiful beaches and historic sites, some caution is recommended, particularly at night. Like any location, there are neighborhoods that are best avoided. It is always advisable to stay in well-traveled areas, keep your belongings secure, and avoid flaunting expensive items in public. Local people are generally friendly and helpful, but it's advisable to learn some basic Spanish or have a translation app ready. Public transport can be a viable option during daytime, but taxis are recommended after dark. Always stay alert and aware of your surroundings.