Public transportation:Very safe
Public transportation in Vatican City, largely being Rome's bus and metro system, is considered to be relatively safe even for solo female travelers. The buses and metro trains are frequently busy, providing a certain level of security. However, as a tourist hotspot, pickpocketing can occur, especially in crowded public transportation, so keep an eye on your belongings. Nevertheless, such incidents are usually non-violent, and overall, many solo female travelers use public transportation in Vatican City without encountering significant safety issues.