Makrinitsa is a relatively safe travel destination, with low crime rates and a friendly local population. It possesses a family-friendly atmosphere, making it ideal for solo female travelers. Local authorities are helpful and approachable, and emergency services are readily available. However, as with any location, general precautions such as staying mindful of personal belongings, having emergency contacts at the ready, and avoiding dimly lit or secluded areas during the night should be undertaken. But overall, Makrinitsa ensures a secure and enjoyable stay.