Karlovy Vary is generally perceived as a safe destination for solo female travelers. Despite its tourist-centric nature, it maintains a low rate of serious crime. However, like in any other city, it's always important to stay alert, be aware of your surroundings, and keep your belongings secure. Instances of petty thefts and scams have been occasionally reported, mostly aligned with opportunistic incidents. As always, making smart, safe choices will help you enjoy what this beautiful spa town has to offer.