Epernay, located in the Champagne region, is widely recognized as safe, especially by day when it's bustled with wine-lovers visiting cellars and vineyards. While crime is relatively low, general safety measures like avoiding quiet and dimly lit areas at night, keeping an eye on personal possessions and not sharing your accommodation details with strangers are advisable. Like many destinations, it's important to exercise typical precautions, but overall, Epernay offers a positive experience for solo female travelers.