Tennessee is generally safe for solo female travelers. Cities like Nashville and Memphis are popular tourist destinations with plenty of well-traveled areas. Like any location, it's always important to exercise common sense, especially at night and in less crowded areas. Law enforcement is typically responsive and there is a good presence of them, especially in tourist areas. Bear in mind that parts of some cities may be less safe than others, so it's recommended to do some research and possibly stay in a reputable hotel in a well-traveled area.