Pascagoula, Mississippi is generally safe for solo female travelers. The city has a welcoming community and it's relatively small so getting around isn't much of a problem. While crime is present as in any city, it’s typically low in areas frequented by tourists. Still, it's important to remain cautious and watchful, especially at night. Avoid isolated areas and always let someone know your itinerary. Overall, taking normal travel precautions should keep you safe in Pascagoula.