Myrtle Beach is generally a safe destination for solo female travelers. Like anywhere, it has areas that are safer than others, so it's important to stay vigilant, especially at night in less crowded places. It's a well-known tourist spot with often many people around which can increase safety, and local authorities are usually on high alert to ensure security. Also, use common sense precautions such as not displaying expensive items openly and always sharing your day's plan with someone trustworthy.