Lexington, can be considered quite safe for solo female travelers. While it's important to maintain awareness of your surroundings at all times anywhere you go, Lexington is widely known for its friendly locals and low crime rates, especially in daylight hours. Night-time can also be safe, but it's better to stick to well-populated areas. As with most places, it's important to use common sense and take standard precautions such as avoiding poorly lit or deserted areas at night.