Griffin is generally a safe destination for solo female travelers. Like any city, it has areas that are safer than others, so make sure you do your research on neighborhoods before you go. Most locals are welcoming and helpful, especially towards tourists. It's recommended to take usual travel precautions, such as not walking alone late at night and staying aware of your surroundings, particularly in less crowded areas. As with any location, it's always wise to stay in well-lit areas and keep your belongings secure at all times.