Gatlinburg, is generally considered safe for solo female travelers. It has a relaxed and friendly atmosphere with a low violent crime rate. During daylight hours, the city is filled with sightseers, so you can feel fairly secure. However, as with any travel destination, it is advised to be cautious, especially at night or in remote tourist areas. The main issue might be unexpected encounters with local wildlife. It's always wise to stay aware of your surroundings and keep to well-populated areas.