Clarksdale, generally presents a moderate level of safety. Like any city, it has areas that are more safe and less safe than others, and it's always advised to remain vigilant and aware of your surroundings. Crime rates are often higher than the national average, but it's worth noting that a significant portion of this is property crime rather than violent crime. In the daytime, many tourists, including solo female travelers, stick to the Downtown area and frequently visit areas like the Delta Blues Museum without major safety concerns. At night, it's advisable to avoid less busy areas and always let someone know your whereabouts. While not inherently unsafe, extra caution when traveling alone is strongly recommended.