Diyarbakir, like many places, has pockets of safety and areas where caution is required. This historical city is typically safe during the day, but additional vigilance is necessary at night. As a solo female traveler, it's recommended to avoid secluded areas and adhere to local customs, especially in dressing modestly. Despite a generally welcoming attitude, political unrest and regional tensions can lead to sporadic protests and flare-ups, so stay updated on the local news. Always inform trusted contacts about your plans and take registered taxis when possible.