Orvieto is a remarkably safe city for solo female travelers. It's a tranquil, historic town with low crime rates. Locals are generally friendly, welcoming, and willing to assist travelers. However, just like any other location, it's advisable to observe usual safety precautions, including avoiding deserted areas, particularly at night, and keeping your valuables secure. Tours and public transports are also commonly used, making travel within the town reliable and safe.