Barletta is generally considered safe for solo female travelers. The city is quite friendly and locals are usually very helpful. However, like anywhere, it's always important to stay vigilant, especially during the night or in less crowded areas. Always keep your personal belongings in sight to prevent any issues with pickpocketing which tends to be the most common issue. Overall, women should feel comfortable traveling solo in Barletta but it's always wise to take standard safety precautions.