Zhuhai is generally safe for solo female travelers. Like many big cities it's important to stay vigilant, especially during nighttime or while in isolated locations, but Zhuhai is known for its low crime rates and the locals are hospitable and respectful. However, due to the language barrier, some may find it challenging to navigate without some basic knowledge of Mandarin or Cantonese language. So, do ensure to have necessary preparations regarding potential communication difficulties.