Shigatse is generally considered safe for solo female travelers. Violent crimes are quite rare, and locals are normally helpful and courteous to tourists. Additionally, it's home to several popular tourist destinations which are well supervised. However, like anywhere, it's wise to practice regular safety precautions. Common issues include petty theft and scams targeting tourists. Always maintain awareness of your belongings and surroundings, especially in crowded places. Also consider using reputable travel guides for touring remote areas.