Hamden, US is generally considered to be a safe city for solo female travelers. Crime rates are relatively low, and the locals are friendly and helpful. Like any other city, it pays to be cautious, particularly at night. Make sure to stick to populated areas and well-lit streets, and always let someone know where you're going just to be on the safe side. Always follow your gut feelings as they can be a good indicator of whether or not you feel safe in a situation. Public transport is reliable and can be used with peace of mind.