Nikolaev is generally safe during the day but precautions should always be considered. It is safe to walk around, even in more remote places, but like in any other city, some areas should be avoided, especially at night. Most locals are friendly and willing to help, but it is advised to be aware of your surroundings. Public transport is reliable but it's recommended to avoid late night rides. Personal belongings should be kept close at all times to avoid pickpocketing. Overall, you can enjoy a safe visit if you exercise usual caution.