Kusadasi is generally safe for solo female travelers. Like many tourist destinations, everyone should be aware of their surroundings and take usual safety precautions. Most locals are friendly and respectful towards tourists. However, a little cautiousness never hurts, especially during the night or in less crowded areas. Always trust your instincts, stick to public places and don't reveal too much personal information to strangers. Use public transportation carefully and always negotiate your fare before getting into a taxi.