Mahasarakham is relatively safe for solo female travelers. Like anywhere, one should exercise normal precautionary measures such as not walking alone late at night in less crowded and unfamiliar areas and always ensuring that family or friends know your location or itinerary. Petty theft is sporadic, and opportunistic crimes are more likely targets. It's recommended to always secure your belongings and choose accommodation in well-lit areas. Thai people are generally friendly and welcoming, and women are respected. Just remember to be aware of your surroundings and trust your instincts.