Koh Samet is generally a safe destination for solo female travelers. The island is known for its friendly locals and laid-back atmosphere, which adds to the feeling of safety. However, as with any travel destination, it is always important to stay vigilant and take usual safety precautions. Petty crimes like bag snatching or pickpocketing can happen, especially in tourist areas. At night, it's best to stay in well-lit areas and avoid isolated locations. Regularly communicate your whereabouts to someone you trust, respect local customs, and follow your instincts to keep yourself safe.