Birgunj, located near the Indian border, is generally safe for solo female travelers, showing a moderate safety level. Most of the locals are friendly to tourists. However, due to possible language barrier, cultural differences, and occasional political unrest, it is recommended to be cautious especially during the night or in isolated areas. The city can also be overcrowded, attracting pickpockets in some areas so it's best to take care of your belongings. Travelling with a local guide or in a group can improve the security situation.