Rehovot, tends to be quite safe for solo female travelers. Like in any other destination, it's important to be aware of your surroundings, especially at night. Yet, the city is generally characterized by a friendly and helpful atmosphere. Local people are usually more than willing to lend a helping hand when needed. Public transportation is reliable and crime rates against tourists are relatively low. However, it's a good idea to stay informed about the political situation in the region, and follow official safety advice.