São Leopoldo, being a small city in Brazil, generally has a safe vibe particularly during the day. As a solo female traveler, exercising standard precautions such as avoiding less populated areas during late evening and night, being aware of your surroundings, and keeping personal belongings secure is advisable. However, the city does not have a reputation for significant crime against tourists. Languages can be a bit of a barrier, which may pose a challenge in times of need.