Santarem in Brazil is a relatively safe city to visit for solo female travelers. Most locals are friendly and helpful towards tourists. However, non-violent petty theft such as pick-pocketing and bag-snatching can happen, especially in crowded places, so it's advisable to stay vigilant and take standard precautions to safeguard your belongings. As a solo female traveler, it's also crucial to avoid isolated areas and avoid traveling at night.