Gramado is generally considered safe for solo female travelers. It is a popular tourist attraction in Brazil known for its Swiss-like architecture and chocolate shops. There's a strong police presence, particularly in high-tourist areas. However, it's always important to take common security precautions: avoid roaming the streets late at night, don't show off expensive belongings, and always keep emergency numbers at hand. In the event of any issue, do not hesitate to contact the local authorities.