Quetzaltenango, often known as Xela, is relatively safe for solo female travelers. Like any city, some areas are better than others, and it's important to stay vigilant, especially at night. Always keep your belongings close to you and avoid showing off expensive items. While most locals are friendly and welcoming, always be aware of your surroundings. The use of common safety measures such as not walking alone at night and not flashing expensive possessions can significantly reduce risks.