Dodecanese, is generally considered safe for solo female travelers. Locals are friendly and always willing to help. Crime rates are lower compared to many other places. However, like in all travel situations, it is always best to take precautions, especially when traveling alone. Despite the generally safe environment, it's always advisable not to display expensive personal belongings and keep a low profile when in crowded places to avoid attracting unwanted attention. Always remain vigilant and wary of your surroundings, especially during the night, and it's a good idea to stick to populated well-lit areas.