Botucatu, located in the state of São Paulo, is generally safe for solo female travelers. It is a smaller, less touristic city known for its university, resulting in a relatively peaceful atmosphere. However, like in all urban areas, it's essential to take common sense precautions, especially at night. This includes staying in well-lit areas, not displaying expensive possessions, and being aware of your surroundings. Common crimes can include pickpocketing or bag snatching but violent crime is less likely. Knowledge of Portuguese will be helpful as not everyone speaks English.