Ca Mau generally offers a safe environment for solo female travelers. Traditional Vietnamese culture is expressed robustly in this part of the country. The locals are helpful, and instances of violent crime targeted towards tourists are minimal to non-existent. However, it is always recommended to be aware of your surroundings, especially during the night, and avoid quiet or poorly lit areas. The place can be bustling with market activities throughout the day which makes it quite safe. It's no different than any other travel destination, precautionary measures should always be taken.