St. John, USVI is generally considered a safe destination for solo female travelers. The locals are friendly and helpful, and the crime rate is relatively low compared to many other popular travel destinations. However, like any other place, it's important to stay vigilant and take sensible precautions. Always be aware of your surroundings, especially when walking alone. Do not flaunt valuable items such as expensive jewelry and electronics. In addition, it's recommended to stay in populated and well-lit areas especially during the night.