Generally, Mwanza is moderately safe for solo female travelers. Tanzania as a whole is considered friendly towards tourists. However, like any other city, there are areas that are safer and others that are less safe. During the day, the city is busy and generally safe to travel around. However, during the night, it's advised to take a trusted taxi. Some areas can get quiet at night and are better avoided solo. Simple precautions such as not flashing expensive items and avoiding deserted areas especially at night can boost your safety. Moreover, adhering to local customs and dress code is recommended for a respectful and safer experience.