Arequipa is generally safe for tourists with a lower crime rate than other major cities in Peru. However, as a solo female traveler, you should take some precautions - always maintain awareness of your surroundings, avoid walking alone at night and keep your belongings secure. Petty thefts can occur, especially in crowded places, so always keep an eye on your luggage and personal items. Try to stay in well-traveled areas, dress modestly, and carry a local map or GPS to help navigate through the city. Local people are usually friendly and more than willing to give directions or advice.