In Telavi, the overall atmosphere is safe and friendly for a solo female traveler. Most locals are very welcoming and respectful. However, it's a good idea to observe usual travel precautions. As for street harassment, it's relatively low. Incidents of catcalling, stalking, or any other forms of street harassment are not common, but it doesn't mean they don't occur at all. Always remain aware of your surroundings and trust your instincts.