San Andrés is generally safe for solo female travelers, especially within the more tourist-friendly areas. However, it is a densely populated area with certain neighborhoods that may not be as safe, particularly for women at night. It is advisable to be cautious, stay in well-lit and bustling areas, and avoid walking alone after dark, if possible. If you do find yourself out late, it's smarter to use a trusted taxi service rather than walking. Like anywhere, maintaining a high level of situational awareness is critical to your safety.