Rio Negro generally possesses a moderate level of safety for solo female travelers. Generally, residents are friendly and the town is calm. However, like any other places, some areas may not be very safe particularly at night. Hence, precautions should be taken. Avoiding secluded areas, not displaying valuables in public, and staying in a reputable hotel can enhance personal security. A respectable knowledge of Spanish can further mitigate risk. As always, researching beforehand about specific places to visit ensures a better understanding of what areas to avoid.