Sen Monorom, though a small city, is generally safe during the day, with friendly locals and a pleasant environment. Common precautions should be taken as petty thefts, like bag snatching, are known to happen in Cambodia. Practice caution particularly at night and avoid isolated areas to ensure personal safety. As the city is a popular tourist destination, scams targeting tourists are a small concern. It is advisable to research thoroughly before booking tours or guides.