Gaborone is generally safe for solo female travelers. Most locals are friendly and respectful, making it comfortable for female travelers to navigate around. There's a visible police presence and emergency services are reliable. However, like in any city, it's important to stay aware of your surroundings, especially at night, to avoid any possible encounters with opportunistic crime. It's also advised to avoid displaying expensive belongings outwardly and keep your personal belongings secure at all times.