Altiplano can be relatively safe for solo female travelers but it's crucial to take certain precautions. Petty crime like pickpocketing and bag-snatching is quite common in crowded areas. It's advised to avoid isolated areas, especially at night. Also, keep in mind that the altitude in Altiplano can be quite high and may take some time to get used to. Good health precautions are, therefore, necessary. The locals are generally very friendly, but do be cautious of those who seem overly helpful. As long as you have a sense of your surroundings, take normal safety precautions, and travel during the day, you should be able to have a positive experience. Remember, your safety lies in your own hands.