Anuradhapura is largely considered safe for solo female travelers. Like any travel destination, it's important to stay cautious and aware of your surroundings. Daytime exploring is generally safe, and as long as standard precautions are taken (i.e., not walking alone at night in desolate areas), you should be able to navigate the area confidently. Public transportation and accommodations are reliable. However, as a solo female traveler, it's recommended to dress modestly in respect of the local culture.