Mtwapa is generally safe for solo female travelers. As with any location, it's always important to stay vigilant and aware of your surroundings, especially during the night. Avoid walking alone during late hours and stick to well-lit, populated areas. It is also advisable to dress modestly respecting the local culture. Interacting with locals can further enrich your travel experience as Kenyan people are generally friendly and helpful. Use trusted transportation services and keep your belongings secure at all times.