Greenland is generally very safe for solo female travelers. The crime rate is low, locals are friendly and helpful, and it's quite easy to navigate. However, it's always wise to be cautious and take general safety measures like avoiding isolated areas during the night and not sharing your personal information with strangers. It's also important to be aware of possible risks related to wilderness activities, such as hiking or boat travel, which are better to be done with a local guide if you're not experienced.