Rio Grande offers a moderate level of safety for solo female travelers. It is a tourist-friendly destination with welcoming locals. Most visitors do not encounter issues, but standard precautions should always be taken. Avoid flashing valuables and walking alone at night in less frequented areas. It's always advisable to stay in well-lit areas and in close proximity to other people, particularly after dark. Just like in any place you travel to, it's good to remain alert and aware of your surroundings.